A handkerchief is usually made of cloth, however, not paper.
手帕通常是用布而不是纸巾做的。
The paper parcel contained a clean shirt, socks and a handkerchief.
纸包里有一件干净的衬衫、短袜和一方手帕。
If you cough, cover your mouth and nose with tissue paper or a handkerchief.
如果你有咳嗽, 请用卫生纸或手帕掩住口鼻。
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